Research interests

1. Molecular hydrogels based on anti-cancer drugs and other therapeutic agents

Cancer chemotherapy is usually necessary and to date remains the best way to reduce the size of solid tumors, eliminate tumor residues and prevent tumor metastasis after surgery. However, anti-cancer drugs such as Taxol and cisplatinum-based drugs frequently suffer from low water solubility and result in adverse side effects. An injectable delivery system that can sustainedly release anti-cancer drugs may improve the efficiency of chemotherapy and prolong the life of patients. Self-delivery system with a high weight percentage of anti-cancer drugs is injectable and can release anti-cancer drugs sustainedly over a long period of time. It might be administrated to the inside of tumors to reduce the their size for patients in a late stage of cancer or administrated in the cavities left by tumor removal to eliminate tumor residues and prevent metastasis.

2. Hybrid hydrogels based on Molecular hydrogels and polymeric hydrogels

3. Cells culture in 2D or 3D environments and other application of tissue engineering

4. Biohybrid hydrogels based on proteins and peptides

Protein-based hydrogels are promising materials for tissue engineering and drug delivery due to the unique property of proteins such as perfect polydispersity, exact control over monomer sequence, ability to fine-tune molecular-level biochemical interactions, etc.rationally designed protein-based hydrogels will have broad applications in many areas including controlled delivery, tissue engineering, drug screening.

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